tumor-suppressor protein

tumor-suppressor protein
белок-подавитель опухоли
белок, кодируемый геном-супрессором опухоли, препятствующий бесконтрольному делению и росту клеток

English-Russian Biotechnology Glossary. . 2007.

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  • Tumor suppressor gene — A tumor suppressor gene, or antioncogene is a gene that protects a cell from one step on the path to cancer. When this gene is mutated to cause a loss or reduction in its function, the cell can progress to cancer, usually in combination with… …   Wikipedia

  • ARF tumor suppressor — The ARF tumor suppressor is a protein that is transcribed from an alternate reading frame of the INK4a/ARF locus (CDKN2A).[1] ARF is induced in response to sustained mitogenic stimulation, such as aberrant growth signaling from MYC and Ras… …   Wikipedia

  • Von Hippel-Lindau tumor suppressor — The Von Hippel Lindau tumor suppressor protein is encoded by the VHL gene and when inactivated is associated with Von Hippel Lindau disease. PBB Summary section title = summary text = Von Hippel Lindau syndrome (VHL) is a dominantly inherited… …   Wikipedia

  • Protéin Tax — Protéine Tax Pour les articles homonymes, voir Tax. La protéine Tax (de Transactivator of pX) est une oncoprotéine virale exprimée par le rétrovirus T lymphotrope humain de type 1 (HTLV 1). Elle a des fonctions de transactivateur transcriptionnel …   Wikipédia en Français

  • Tumor antigen — is a substance produced in tumor cells that triggers an immune response in the host. Tumor antigens are useful in identifying tumor cells and are potential candidates for use in cancer therapy. Mechanism of tumor antigenesisNormal proteins in the …   Wikipedia

  • Protein arginine methyltransferase 5 — Protein arginine methyltransferase 5, also known as PRMT5, is a human gene.cite web | title = Entrez Gene: PRMT5 protein arginine methyltransferase 5| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene Cmd=ShowDetailView TermToSearch=10419|… …   Wikipedia

  • Merlin (protein) — Neurofibromin 2 (merlin) PDB rendering based on 1h4r …   Wikipedia

  • Retinoblastoma protein — The retinoblastoma protein (abbreviated pRb or Rb ) is a tumor suppressor protein that is dysfunctional in many types of cancer.Murphree A.L. and Benedict W.F. 1984. Retinoblastoma: clues to human oncogenesis in Science , 223(4640): 1028 1033.… …   Wikipedia

  • Retinoblastom-Protein — RB 1 Bändermodell der Domain A von RB (Aminosäuren 378 562) nach PDB  …   Deutsch Wikipedia

  • E6 - protein — The E6 protein is one of the key cancer causing proteins expressed by the Human papillomavirus (HPV). Among the strains of HPV known to cause physical changes associated with cancer and pre cancerous lesions, three oncoproteins are recognized: E5 …   Wikipedia

  • Retinoblastoma-like protein 1 — Retinoblastoma like 1 (p107), also known as RBL1, is a human gene. PBB Summary section title = summary text = The protein encoded by this gene is similar in sequence and possibly function to the product of the retinoblastoma 1 (RB1) gene. The RB1 …   Wikipedia


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